Poultry are constantly being bombarded by pathogens, resulting in being in a constant inflammatory state. This energy consuming process can have a detrimental effect on health and production, not to mention additional stressors caused by several factors. So, what happens inside the bird when inflammation kicks in?

  1. The GIT serves as a selective barrier to take up nutrients and fluids into the body, while excluding undesirable molecules and pathogens (Vicuna, 2015).
  2. Proper gut barrier function is essential to maintain optimal health and balance
               throughout the body and is the first line of defense against foreign antigens
               from the environment (Vicuna, 2015).
  3. Oxidative stress, poorly digestible protein or energy sources and coccidiosis
             are some examples that can cause gut barrier failure (Vicuna, 2015).
  4. Commercial poultry are exposed to many stressors that can induce changes in
             gut motility and permeability, as well as possible alterations in mucus secretion
               and absorption (Vicuna, 2015).
  5. These changes have been linked to Mast cells, translating stress signals into
             the release of neurotransmitters and pro-inflammatory cytokines, with dramatic
               effects on gastrointestinal physiology (Vicuna, 2015).
  6. Enteric inflammation stress increases gut leakage associated with dissolution
             of tight junctions between endocrine cells (Vicuna, 2015).

Xtract Nature is known for its effect on immunity of poultry, by depressing innate and stimulating acquired immunity in birds through the actions of Capsicum and Curcuma respectively. With downregulation of inflammatory cytokines and stimulation of more antibodies and a thicker mucus layer in the gut, Xtract Nature is an excellent natural product to enhance the functionality of vaccinations, providing extra protection against virucidal and bacterial challenges in broilers, breeders and layer birds.

At a low inclusion rate of 100g/t of feed, several trials have proven its efficacy and today, Xtract Nature is being applied worldwide in monogastric production systems.

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